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I.d

I - Interstitial/parenchymal lung disease

Acute eosinophilic pneumonia (AEP)

Last update 05/09/2023

(Fr: PnP aiguë à éosinophiles). See also under Ic: 'Eosinophilic pneumonia'. May cause ARF and ARDS. MV and/or ECMO may be needed. AEP is with diffuse pulmonary opacities, blood/BAL eosinophilia, pleural effusion and rapidly-progressive respiratory failure in the absence of a cause other than a drug or abused substance (e.g. parasitic infection). See also under IIb and XVb. Separating drug-induced vs. idiopathic AEP can be problematic (PMID 2761601; 29369189)

Causative drugs

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases