The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Kaslow JA, Snyder EJ, Bridges BC, Rosas-Salazar C

Massive Facial, Neck, and Chest Air Leaks after Amoxicillin-related Anaphylaxis in a Young Child.

American journal of respiratory and critical care medicine. 2020;201(7):859-860

Azevedo J, Gaspar Â, Mota I, Benito-Garcia F, Alves-Correia M, Chambel M, Morais-Almeida M

Anaphylaxis to beta-lactam antibiotics at pediatric age: Six-year survey.

Allergologia et immunopathologia. 2019;47(2):128-132

Renaudin JM, Beaudouin E, Ponvert C, Demoly P, Moneret-Vautrin DA

Severe drug-induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010.

Allergy. 2013;68(7):929-37

da Fonseca MA

Adverse reaction to amoxicillin: a case report.

Pediatric dentistry. 2000;22(5):401-4