The Drug-Induced Respiratory Disease Website and App

Abused drugs/substances (illicit-, street drugs - IV/inhaled)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Martín-Macho González M, López Hormiga D, Cívico Martín E

Pulmonary complications for drug consumption: Diffuse alveolar hemorrhage.

Medicina intensiva 2021 Nov 01;; — 2021 Nov 01

Yamanoglu A, Cakmak S, Celebi Yamanoglu NG, Sogut O

A new side effect of synthetic cannabinoid use by the bucket (waterpipe) method: Acute respiratory distress syndrome (ARDS).

Turkish journal of emergency medicine 2018 Mar;18;42-44 — 2018 Mar — 42-44

de Prost N, Parrot A, Cuquemelle E, Picard C, Antoine M, Fleury-Feith J, Mayaud C, Boffa JJ, Fartoukh M, Cadranel J

Diffuse alveolar hemorrhage in immunocompetent patients: etiologies and prognosis revisited.

Respiratory medicine 2012 Jul;106;1021-32 — 2012 Jul — 1021-32

Todorovi? MS, Mitrovi? S, Aleksandri? B, Mladjenovi? N, Mateji? S

Association of pulmonary histopathological findings with toxicological findings in forensic autopsies of illicit drug users.

Vojnosanitetski pregled 2011 Aug;68;639-42 — 2011 Aug — 639-42

Grassin F, André M, Rallec B, Combes E, Vinsonneau U, Paleiron N

[Fatal alveolar haemorrhage following a "bang" of cannabis].

Revue des maladies respiratoires 2011 Sep;28;919-23 — 2011 Sep — 919-23

Porter R, O'Reilly H

Pulmonary hemorrhage: a rare complication of opioid overdose.

Pediatric emergency care 2011 Aug;27;742-4 — 2011 Aug — 742-4

Restrepo CS, Artunduaga M, Carrillo JA, Rivera AL, Ojeda P, Martinez-Jimenez S, Manzano AC, Rossi SE

Silicone pulmonary embolism: report of 10 cases and review of the literature.

Journal of computer assisted tomography 2009 Mar-Apr;33;233-7 — 2009 Mar-Apr — 233-7