The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Desquamative interstitial pneumonia (DIP-pattern)
Publications
Desquamative interstitial pneumonia.
Histopathology 2011 Mar;58;509-16 — 2011 Mar — 509-16
Interstitial pneumonitis with accumulation of intraalveolar macrophages, a facet amiodarone therapy.
Clinical research in cardiology : official journal of the German Cardiac Society 2008 Dec;97;917-20 — 2008 Dec — 917-20
Histiocytic lesions and proliferations in the lung.
Seminars in diagnostic pathology 2007 Aug;24;162-82 — 2007 Aug — 162-82