The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.ay

Chronic pneumonitis

Publications

Budin CE, Cocuz IG, Sab?u AH, Niculescu R, Ianosi IR, Ioan V, Cotoi OS

Pulmonary Fibrosis Related to Amiodarone-Is It a Standard Pathophysiological Pattern? A Case-Based Literature Review.

Diagnostics (Basel, Switzerland) 2022 Dec 19;12; — 2022 Dec 19

Suárez LD, Poderoso JJ, Elsner B, Bunster AM, Esteva H, Bellotti M

Subacute pneumopathy during amiodarone therapy.

Chest 1983 Mar;83;566-8 — 1983 Mar — 566-8