The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.d

Acute eosinophilic pneumonia (AEP)

Publications

García-Moguel I, Bobolea I, Diéguez Pastor MC, López-Arranz Monge G, Barranco Jimenez R

Acute eosinophilic pneumonia due to piperacillin/tazobactam.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2019 Mar;122;334-336 — 2019 Mar — 334-336

Foong KS, Lee A, Pekez M, Bin W

Imipenem/cilastatin-induced acute eosinophilic pneumonia.

BMJ case reports 2016 Mar 04;2016; — 2016 Mar 04

Rether C, Conen A, Grossenbacher M, Albrich WC

A rare cause of pulmonary infiltrates one should be aware of: a case of daptomycin-induced acute eosinophilic pneumonia.

Infection 2011 Dec;39;583-5 — 2011 Dec — 583-5