The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIX.ak

Path: Smudged geographic necrosis

Publications

Kimura T, Kuramochi S, Katayama T, Yoshikawa T, Yamada T, Ueda Y, Okada Y

Amiodarone-related pulmonary mass and unique membranous glomerulonephritis in a patient with valvular heart disease: Diagnostic pitfall and new findings.

Pathology international 2008 Oct;58;657-63 — 2008 Oct — 657-63

Ruangchira-Urai R, Colby TV, Klein J, Nielsen GP, Kradin RL, Mark EJ

Nodular amiodarone lung disease.

The American journal of surgical pathology 2008 Nov;32;1654-60 — 2008 Nov — 1654-60