The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.t

A mass or masses

Publications

Carvalho JG, Fernandes C, França M

Organizing pneumonia secondary to amiodarone treatment.

Heliyon 2022 Sep;8;e10630 — 2022 Sep — e10630

Ruangchira-Urai R, Colby TV, Klein J, Nielsen GP, Kradin RL, Mark EJ

Nodular amiodarone lung disease.

The American journal of surgical pathology 2008 Nov;32;1654-60 — 2008 Nov — 1654-60

Jarand J, Lee A, Leigh R

Amiodaronoma: an unusual form of amiodarone-induced pulmonary toxicity.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2007 May 08;176;1411-3 — 2007 May 08 — 1411-3

Arnon R, Raz I, Chajek-Shaul T, Berkman N, Fields S, Bar-On H

Amiodarone pulmonary toxicity presenting as a solitary lung mass.

Chest 1988 Feb;93;425-7 — 1988 Feb — 425-7