The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.a

DRES syndrome - DRESS-like reaction

Publications

Jung HY, Park S, Shin B, Lee JH, Lee SJ, Lee MK, Lee WY, Yong SJ, Kim SH

Prevalence and Clinical Features of Drug Reactions With Eosinophilia and Systemic Symptoms Syndrome Caused by Antituberculosis Drugs: A Retrospective Cohort Study.

Allergy, asthma & immunology research 2019 Jan;11;90-103 — 2019 Jan — 90-103

Kaswala DH

Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Due to Anti-TB Medication.

Journal of family medicine and primary care 2013 Jan;2;83-5 — 2013 Jan — 83-5

Nam YH, Park MR, Nam HJ, Lee SK, Kim KH, Roh MS, Um SJ, Son CH

Drug reaction with eosinophilia and systemic symptoms syndrome is not uncommon and shows better clinical outcome than generally recognised.

Allergologia et immunopathologia 2015 Jan-Feb;43;19-24 — 2015 Jan-Feb — 19-24