The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Eye catcher: Electron-dense area or areas of consolidation on unenhanced chest CT
Publications
Amiodarone-induced hepatic and pulmonary toxicity.
Postgraduate medical journal 2018 Oct;94;603 — 2018 Oct — 603
An enlarged heart with hyperdense consolidation.
The Netherlands journal of medicine 2013 Jul-Aug;71;317, 321 — 2013 Jul-Aug — 317, 321