The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LV.ba

Imaging: Asymmetrical, predominantly unilateral involvement

Publications

Chen J, Hinton S

Acute amiodarone interstitial toxicity presenting as unilateral pneumonitis.

BMJ case reports 2021 Dec 31;14; — 2021 Dec 31

Camus P, Lombard JN, Perrichon M, Piard F, Guérin JC, Thivolet FB, Jeannin L

Bronchiolitis obliterans organising pneumonia in patients taking acebutolol or amiodarone.

Thorax 1989 Sep;44;711-5 — 1989 Sep — 711-5