The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Knudsen L, Gugger M, Dumont P, Nicod L, von Garnier C

A rare cause of acute respiratory failure and elevated eosinophils in broncho-alveolar lavage fluid.

Respiration; international review of thoracic diseases. 2009;77(2):224-8

Katsenos S, Psathakis K, Nikolopoulou MI, Constantopoulos SH

Mefloquine-induced eosinophilic pneumonia.

Pharmacotherapy. 2007;27(12):1767-71

Mitja K, Izidor K, Music E

[Chloroquine-induced drug hypersensitivity alveolitis].

Pneumologie (Stuttgart, Germany). 2000;54(9):395-7

Jedynak U, Ciezarek M, Kopiński P

Pulmonary infiltrates with masto- and lymphocytosis in BALF associated with arechine.

Polish journal of pathology : official journal of the Polish Society of Pathologists. 1997;48(1):63-7

Davidson AC, Bateman C, Shovlin C, Marrinan M, Burton GH, Cameron IR

Pulmonary toxicity of malaria prophylaxis.

BMJ (Clinical research ed.). 1988;297(6658):1240-1