The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIX.a

Path: NSIP-cellular pattern (see also Ia, Ib)

Publications

Shi JH, Liu HR, Zhu YJ, Xu WB

[Clinicopathologic manifestation of amiodarone-induced lung injury].

Zhonghua bing li xue za zhi = Chinese journal of pathology 2006 Jul;35;394-7 — 2006 Jul — 394-7

Papiris SA, Maniati MA, Manoussakis MN, Constantopoulos SH

Orthodeoxia in amiodarone-induced acute reversible pulmonary damage.

Chest 1994 Mar;105;965-6 — 1994 Mar — 965-6