The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Foreign body deposits/granulomatous reaction
Publications
Pulmonary talcosis with intravenous drug abuse.
Respiratory care. 2013;58(10):e126-8
Weinkauf JG, Puttagunta L, Nador R, Jackson K, LaBranche K, Kapasi A, Mullen J, Modry DL, Stewart KC, Thakrar M, Doucette K, Lien DC
Long-term outcome of lung transplantation in previous intravenous drug users with talc lung granulomatosis.
Transplantation proceedings. 2013;45(6):2375-7
Widespread pulmonary granulomatosis following long time intravenous drug abuse--a case report.
Forensic science international. 2010;197(1-3):e27-30