The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LV.w

Imaging: Lung nodule or nodules

Publications

Kugasia IR, Ijaz M, Khan A, Jasti Y

Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis.

The American journal of case reports 2020 Oct 23;21;e926929 — 2020 Oct 23 — e926929

Griffith C, Hossain S, Minupuri A, Korman M

Nodules that Wax and Wane: Unusual Presentation of Amiodarone Lung Toxicity.

Cureus 2020 Jul 08;12;e9058 — 2020 Jul 08 — e9058

Jarand J, Lee A, Leigh R

Amiodaronoma: an unusual form of amiodarone-induced pulmonary toxicity.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2007 May 08;176;1411-3 — 2007 May 08 — 1411-3