The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.x

Rapidly progressive ILD/pulmonary fibrosis (Hamman-Rich syndrome)

Publications

Newmarch W, Puopolo A, Weiler M, Casserly B

Hamman-Rich syndrome: a forgotten entity.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 2017 05 18;87;799 — 2017 05 18 — 799

Kharabsheh S, Abendroth CS, Kozak M

Fatal pulmonary toxicity occurring within two weeks of initiation of amiodarone.

The American journal of cardiology 2002 Apr 01;89;896-8 — 2002 Apr 01 — 896-8