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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.at

Amiodarone pulmonary toxicity - Amiodarone lung

See under PMID 15062598 (review), 29631763 (Pathology) and Camus, Ph., T.V. Colby, E.C.I. Rosenow, Amiodarone pulmonary toxicity. In Drug-induced and iatrogenic lung disease. P. Camus and E.C. Rosenow, Editors. 2010, Hodder Arnold: London UK

Publications

Roden AC, Camus P

Iatrogenic pulmonary lesions.

Seminars in diagnostic pathology. 2018;35(4):260-271

Camus P, Martin WJ 2nd, Rosenow EC 3rd

Amiodarone pulmonary toxicity.

Clinics in chest medicine. 2004;25(1):65-75

Bedrossian CW, Warren CJ, Ohar J, Bhan R

Amiodarone pulmonary toxicity: cytopathology, ultrastructure, and immunocytochemistry.

Annals of diagnostic pathology. 1997;1(1):47-56

Dezile G, Roullier A, Arbeille-Brassart B

[Interstitial pneumopathy in subjects treated with amiodarone].

Presse medicale (Paris, France : 1983). 1983;12(43):2747-50

Dean PJ, Groshart KD, Porterfield JG, Iansmith DH, Golden EB Jr

Amiodarone-associated pulmonary toxicity. A clinical and pathologic study of eleven cases.

American journal of clinical pathology. 1987;87(1):7-13

Martin WJ 2nd, Rosenow EC 3rd

Amiodarone pulmonary toxicity. Recognition and pathogenesis (Part 2).

Chest. 1988;93(6):1242-8

Martin WJ 2nd, Rosenow EC 3rd

Amiodarone pulmonary toxicity. Recognition and pathogenesis (Part I).

Chest. 1988;93(5):1067-75