The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Kozlova N, Lanier G, Kleinman G, Epelbaum O

Acute amiodarone pulmonary toxicity in the form of organizing pneumonia triggered by orthotopic heart transplantation.

Respiratory medicine case reports 2021;34;101532 — 2021 — 101532

Terzo F, Ricci A, D'Ascanio M, Raffa S, Mariotta S

Amiodarone-induced pulmonary toxicity with an excellent response to treatment: A case report.

Respiratory medicine case reports 2020;29;100974 — 2020 — 100974

Van Cott TE, Yehle KS, DeCrane SK, Thorlton JR

Amiodarone-induced pulmonary toxicity: case study with syndrome analysis.

Heart & lung : the journal of critical care 2013 Jul-Aug;42;262-6 — 2013 Jul-Aug — 262-6

Hudzik B, Polonski L

Amiodarone-induced pulmonary toxicity.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2012 Oct 16;184;E819 — 2012 Oct 16 — E819

Rotmensch HH, Liron M, Tupilski M, Laniado S

Possible association of pneumonitis with amiodarone therapy.

American heart journal 1980 Sep;100;412-3 — 1980 Sep — 412-3

Shen ZL, Yuan XZ, Gu XR, Zhou JS, Xia SR, Ding ZG, Zong XY, Hong YX, Deng SS, Song CC

[Studies on criteria of transmission-interruption of filariasis due to Brugia malayi].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases — 1987 — 294-6