The Drug-Induced Respiratory Disease Website and App

Abused drugs/substances (illicit-, street drugs - IV/inhaled)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Nasal, palatal and/or pharyngeal pathology

Publications

Houlton JJ, Donaldson AM, Zimmer L, Seiden A

Intranasal drug-induced fungal rhinopharyngitis.

International forum of allergy & rhinology 2012 Mar-Apr;2;130-4 — 2012 Mar-Apr — 130-4

Myon L, Delforge A, Raoul G, Ferri J

[Palatal necrosis due to cocaine abuse].

Revue de stomatologie et de chirurgie maxillo-faciale 2010 Feb;111;32-5 — 2010 Feb — 32-5

Rachapalli SM, Kiely PD

Cocaine-induced midline destructive lesions mimicking ENT-limited Wegener's granulomatosis.

Scandinavian journal of rheumatology 2008 Nov-Dec;37;477-80 — 2008 Nov-Dec — 477-80

Scheenstra RJ, van Buren M, Koopman JP

[A patient with both cocaine-induced nasal septum destruction and antibodies against anti-neutrophil cytoplasmic antibodies (ANCA); potential confusion with Wegener's disease].

Nederlands tijdschrift voor geneeskunde 2007 Oct 27;151;2395-9 — 2007 Oct 27 — 2395-9

Di Cosola M, Turco M, Acero J, Navarro-Vila C, Cortelazzi R

Cocaine-related syndrome and palatal reconstruction: report of a series of cases.

International journal of oral and maxillofacial surgery 2007 Aug;36;721-7 — 2007 Aug — 721-7

Seyer BA, Grist W, Muller S

Aggressive destructive midfacial lesion from cocaine abuse.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2002 Oct;94;465-70 — 2002 Oct — 465-70

Gendeh BS, Ferguson BJ, Johnson JT, Kapadia S

Progressive septal and palatal perforation secondary to intranasal cocaine abuse.

The Medical journal of Malaysia 1998 Dec;53;435-8 — 1998 Dec — 435-8

Sevinsky LD, Woscoff A, Jaimovich L, Terzian A

Nasal cocaine abuse mimicking midline granuloma.

Journal of the American Academy of Dermatology 1995 Feb;32;286-7 — 1995 Feb — 286-7

Daggett RB, Haghighi P, Terkeltaub RA

Nasal cocaine abuse causing an aggressive midline intranasal and pharyngeal destructive process mimicking midline reticulosis and limited Wegener's granulomatosis.

The Journal of rheumatology 1990 Jun;17;838-40 — 1990 Jun — 838-40