The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.d

Pleural/pericardial effusion, ANA positive (DI lupus)

Publications

Kundu AK

Amiodarone-induced systemic lupus erythematosus.

The Journal of the Association of Physicians of India 2003 Feb;51;216-7 — 2003 Feb — 216-7

Sheikhzadeh A, Schäfer U, Schnabel A

Drug-induced lupus erythematosus by amiodarone.

Archives of internal medicine 2002 Apr 08;162;834-6 — 2002 Apr 08 — 834-6

Susano R, Caminal L, Ramos D, Díaz B

Amiodarone induced lupus.

Annals of the rheumatic diseases 1999 Oct;58;655-6 — 1999 Oct — 655-6