The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Associated with intravenous administration of the drug
Publications
Anaphylactic shock associated with intravenous amiodarone.
Journal of cardiology cases. 2014;9(2):61-62
Anaphylactic shock after amiodarone infusion resulting in haemodynamic collapse requiring a temporary ventricular assist device.
Cardiology in the young. 2015;25(1):164-6
Anaphylaxis during intravenous administration of amiodarone.
Annals of cardiac anaesthesia. 2013;16(3):229-30
Anaphylactic shock due to intravenous amiodarone.
The American journal of emergency medicine. 2012;30(1):265.e1-2