The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Lung abscess/abscesses (see also VIr)
Typically found in IV drug users. Abcesses may reveal undelying right-sided bacterial endocarditis
Publications
The large spectrum of pulmonary complications following illicit drug use: features and mechanisms.
Chemico-biological interactions 2013 Dec 05;206;444-51 — 2013 Dec 05 — 444-51
Tricuspid Endocarditis and Septic Pulmonary Embolism in an Intravenous Drug User with advanced HIV Infection.
Oman medical journal 2011 Sep;26;365-7 — 2011 Sep — 365-7
The histopathology of drugs of abuse.
Histopathology 2011 Oct;59;579-93 — 2011 Oct — 579-93
Taylor A, Hutchinson S, Lingappa J, Wadd S, Ahmed S, Gruer L, Taylor TH, Roy K, Gilchrist G, McGuigan C, Penrice G, Goldberg D
Severe illness and death among injecting drug users in Scotland: a case-control study.
Epidemiology and infection 2005 Apr;133;193-204 — 2005 Apr — 193-204
Complications of attempted central venous injections performed by drug abusers.
Chest 1980 Oct;78;613-7 — 1980 Oct — 613-7