The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Lung abscess/abscesses (see also VIr)
Typically found in IV drug users. Abcesses may reveal undelying right-sided bacterial endocarditis
Publications
The large spectrum of pulmonary complications following illicit drug use: features and mechanisms.
Chemico-biological interactions. 2013;206(3):444-51
Tricuspid Endocarditis and Septic Pulmonary Embolism in an Intravenous Drug User with advanced HIV Infection.
Oman medical journal. 2011;26(5):365-7
The histopathology of drugs of abuse.
Histopathology. 2011;59(4):579-93
Taylor A, Hutchinson S, Lingappa J, Wadd S, Ahmed S, Gruer L, Taylor TH Jr, Roy K, Gilchrist G, McGuigan C, Penrice G, Goldberg D
Severe illness and death among injecting drug users in Scotland: a case-control study.
Epidemiology and infection. 2005;133(2):193-204
Complications of attempted central venous injections performed by drug abusers.
Chest. 1980;78(4):613-7