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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.ab

Pneumothorax, bilateral

May reveal/complicate septic pulmonary emboli (PMID 2225993)

Publications

Maeder M, Ullmer E

Pneumomediastinum and bilateral pneumothorax as a complication of cocaine smoking.

Respiration; international review of thoracic diseases. 2003;70(4):407

Cantan R, Milesi-Defrance N, Hardenberg K, Vernet M, Messant I, Freysz M

[Bilateral pneumothorax and tamponade after acupuncture].

Presse medicale (Paris, France : 1983). 2003;32(7):311-2

Filosso PL, Arslanian A, Ruffini E, Mancuso M

Bilateral pneumothorax, pneumonia, and pneumomediastinum after injection of a hard drug into the neck.

The Journal of thoracic and cardiovascular surgery. 2002;124(6):1233-4

Cohen HL, Cohen SW

Spontaneous bilateral pneumothorax in drug addicts.

Chest. 1984;86(4):645-7

Savitt D, Oblinger P, Levy RC

Bilateral pneumothorax in an intravenous drug abuser.

The Journal of emergency medicine. 1985;2(6):405-8