The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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Pericardial effusion (w/wo tamponade)

Publications

Abrams JL, Fermi D, Belligund P, McFarlane SI

Amiodarone-Induced Hypothyroidism Related to Pericardial Effusion With Tamponade Physiology.

Cureus 2022 Mar;14;e22932 — 2022 Mar

Motabar A, Anousheh R, Shaker R, Pai RG

A rare case of amiodarone-induced hypothyroidism presenting with cardiac tamponade.

The International journal of angiology : official publication of the International College of Angiology, Inc 2011 Sep;20;177-80 — 2011 Sep — 177-80