The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Path: Foreign body embolism, microangiopathy, vasculopathy
Publications
The clinical picture: an intravenous drug user with persistent dyspnea and lung infiltrates.
Cleveland Clinic journal of medicine. 2014;81(4):223-4
Transbronchial biopsy interpretation in the patient with diffuse parenchymal lung disease.
Archives of pathology & laboratory medicine. 2007;131(3):407-23
ANGIOTHROMBOTIC PULMONARY HYPERTENSION IN ADDICTS. "BLUE VELVET" ADDICTION.
JAMA. 1964;188:755-7
Pulmonary angiothrombotic granulomatosis in drug offenders.
JAMA. 1972;221(8):909-11
Talc: understanding its manifestations in the chest.
AJR. American journal of roentgenology. 1986;146(2):295-301