The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.c

Hemoptysis

Publications

Busch CD, Heiberger CJ, Mehta TI, Yim D

Amiodarone-induced Hemoptysis: A Rare Presentation of Amiodarone-induced Pulmonary Toxicity Occurs at a Low Dose.

Cureus 2019 Jul 31;11;e5289 — 2019 Jul 31 — e5289

Elikowski W, Cofta S, Nowicki A, Ma?czak J, Psuja P

[Recurrent hemoptysis following thienopyridines and amiodarone administration. therapeutic dilemma].

Polskie Archiwum Medycyny Wewnetrznej 2005 Aug;114;773-8 — 2005 Aug — 773-8

Ravishankar R, Samuels LE, Kaufman MS, Samuels FL, Thomas MP, Galindo L, Morris RJ, Brockman SK

Amiodarone-associated hemoptysis.

The American journal of the medical sciences 1998 Dec;316;390-2 — 1998 Dec — 390-2

Goldstein I, Topilsky M, Segev D, Isakov A, Heller I

Very early onset of acute amiodarone pulmonary toxicity presenting with hemoptysis.

Chest 1997 May;111;1446-7 — 1997 May — 1446-7

Vizioli LD, Cho S

Amiodarone-associated hemoptysis.

Chest 1994 Jan;105;305-6 — 1994 Jan — 305-6