The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.c

Hemoptysis

Publications

Busch CD, Heiberger CJ, Mehta TI, Yim D

Amiodarone-induced Hemoptysis: A Rare Presentation of Amiodarone-induced Pulmonary Toxicity Occurs at a Low Dose.

Cureus. 2019;11(7):e5289

Elikowski W, Cofta S, Nowicki A, Mańczak J, Psuja P

[Recurrent hemoptysis following thienopyridines and amiodarone administration. therapeutic dilemma].

Polskie Archiwum Medycyny Wewnetrznej. 2005;114(2):773-8

Ravishankar R, Samuels LE, Kaufman MS, Samuels FL, Thomas MP, Galindo L, Morris RJ, Brockman SK

Amiodarone-associated hemoptysis.

The American journal of the medical sciences. 1998;316(6):390-2

Goldstein I, Topilsky M, Segev D, Isakov A, Heller I

Very early onset of acute amiodarone pulmonary toxicity presenting with hemoptysis.

Chest. 1997;111(5):1446-7

Vizioli LD, Cho S

Amiodarone-associated hemoptysis.

Chest. 1994;105(1):305-6