The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anti-GBM antibody disease (Goodpasture-like or flare of preexisting GS)
Publications
Lazor R, Bigay-Gamé L, Cottin V, Cadranel J, Decaux O, Fellrath JM, Cordier JF, Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires (GERMOP) and the Swiss Group for Interstitial and Orphan Lung Diseases (SIOLD)
Alveolar hemorrhage in anti-basement membrane antibody disease: a series of 28 cases.
Medicine. 2007;86(3):181-193