The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Organizing pneumonia pattern (an area or areas of consolidation on imaging)
Publications
Bronchiolitis obliterans and organising pneumonia caused by carbamazepine and mimicking community acquired pneumonia.
Postgraduate medical journal 2002 Oct;78;621-2 — 2002 Oct — 621-2
Lupus and pulmonary nodules consistent with bronchiolitis obliterans organizing pneumonia induced by carbamazepine.
Mayo Clinic proceedings 1997 Dec;72;1145-7 — 1997 Dec — 1145-7
Bronchiolitis obliterans with organizing pneumonia and cold agglutinin disease associated with phenytoin hypersensitivity syndrome.
Chest 1997 Dec;112;1697-9 — 1997 Dec — 1697-9
Cyclophosphamide in severe steroid-resistant bronchiolitis obliterans organizing pneumonia.
Respiratory medicine 1997 Mar;91;175-7 — 1997 Mar — 175-7