The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Death following exposure or poisoning
Publications
Association of pulmonary histopathological findings with toxicological findings in forensic autopsies of illicit drug users.
Vojnosanitetski pregled. 2011;68(8):639-42
A flood of opioids, a rising tide of deaths.
The New England journal of medicine. 2010;363(21):1981-5
Ingestion of drugs by "parachuting": a unique drug delivery technique.
The American journal of forensic medicine and pathology. 2012;33(2):173-5