The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

Publications

Nicol JJ, Yarema MC, Jones GR, Martz W, Purssell RA, MacDonald JC, Wishart I, Durigon M, Tzemis D, Buxton JA

Deaths from exposure to paramethoxymethamphetamine in Alberta and British Columbia, Canada: a case series.

CMAJ open 2015 Jan-Mar;3;E83-90 — 2015 Jan-Mar — E83-90

Maury E, Darondel JM, Buisinne A, Guitton C, Offenstadt G

Acute pulmonary edema following amphetamine ingestion.

Intensive care medicine 1999 Mar;25;332-3 — 1999 Mar — 332-3

Albertson TE, Walby WF, Derlet RW

Stimulant-induced pulmonary toxicity.

Chest 1995 Oct;108;1140-9 — 1995 Oct — 1140-9