The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

V.d

Pleural/pericardial effusion, ANA positive (DI lupus)

Publications

Wittchen F, Spencker S, Zinke S, Coban N, Schultheiss HP, Witzenbichler B

[Chest pain, reduced physical activity, and polyserositis in a 35-year old patient with anticonvulsive medication].

Der Internist. 2006;47(1):69-75

Verma SP, Yunis N, Lekos A, Crausman RS

Carbamazepine-induced systemic lupus erythematosus presenting as cardiac tamponade.

Chest. 2000;117(2):597-8

Bateman DE

Carbamazepine induced systemic lupus erythematosus: case report.

British medical journal (Clinical research ed.). 1985;291(6496):632-3

Drory VE, Yust I, Korczyn AD

Carbamazepine-induced systemic lupus erythematosus.

Clinical neuropharmacology. 1989;12(2):115-8