The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Bani Salem M, Virk S, Alzoubi Y, Faruqi I

Acute Eosinophilic Pneumonia Triggered by Carbamazepine Therapy: A Clinical and Radiologic Case Report.

Cureus 2026 May;18;e108598 — 2026 May

Archibald N, Yates B, Murphy D, Black F, Lordan J, Dark J, Corris PA

Carbamazepine-induced interstitial pneumonitis in a lung transplant patient.

Respiratory medicine 2006 Sep;100;1660-2 — 2006 Sep — 1660-2

Orliaguet O, Langin T, Gavazzi G, Brambilla C

[Acute eosinophilic pneumonia due to hypersensitivity to carbamazepine].

Revue des maladies respiratoires 1998 Dec;15;797-9 — 1998 Dec — 797-9

Lee T, Cochrane GM, Amlot P

Pulmonary eosinophilia and asthma associated with carbamazepine.

British medical journal (Clinical research ed.) 1981 Feb 07;282;440 — 1981 Feb 07 — 440

Tolmie J, Steer CR, Edmunds AT

Pulmonary eosinophilia associated with carbamazepine.

Archives of disease in childhood 1983 Oct;58;833-4 — 1983 Oct — 833-4

Paladini G, Marinig L

[Immuno-allergic side effects induced by the administration of carbamazepine. Case contribution].

Minerva medica 1984 Jun 30;75;1651-5 — 1984 Jun 30 — 1651-5

Barreiro B, Manresa F, Valldeperas J

Carbamazepine and the lung.

The European respiratory journal 1990 Sep;3;930-1 — 1990 Sep — 930-1

Cullinan SA, Bower GC

Acute pulmonary hypersensitivity to carbamazepine.

Chest 1975 Oct;68;580-1 — 1975 Oct — 580-1

Stephan WC, Parks RD, Tempest B

Acute hypersensitivity pneumonitis associated with carbamazepine therapy.

Chest 1978 Oct;74;463-4 — 1978 Oct — 463-4