Philippe Camus, M.D.

Dijon, France

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XII.af

XII - Cardiovascular involvement / toxicity

Coronary vasospasm - Vasospastic angina

Last update 06/09/2020

Classically in the form of acute ST changes on EKG, acute coronary event or MI (See under XIIg). After episode, coronary bed/angiogram returns to the patent state. May happen without preexisting/underlying CAD

Causative drugs

21

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Adrenaline (epinephrine)
II.a
II.d
II.i
XI.b
XI.d
XII.e
XII.f
XII.g
XII.j
XII.l
XII.t
XII.w
XII.af
XII.aq
Amiodarone
I.a
I.b
I.c
I.d
I.e
I.f
I.g
I.h
I.k
I.l
I.s
I.u
I.w
I.z
I.aa
I.ao
I.at
I.ax
I.ay
II.b
II.l
III.a
III.c
IV.a
IV.d
IV.r
V.a
V.c
V.d
V.t
VI.a
VI.i
VIII.a
IX.a
IX.d
IX.ai
X.d
X.f
X.q
XI.c
XI.f
XII.a
XII.c
XII.e
XII.l
XII.n
XII.p
XII.t
XII.af
XII.au
XV.a
XV.b
XV.c
XV.d
XV.f
XV.g
XV.h
XV.i
XV.j
XV.k
XV.m
XV.o
XV.r
XV.ao
XV.bt
XV.co
XV.dc
XVI.b
XVI.i
XVI.j
XVI.n
XVI.s
XVI.w
XVI.aa
XVI.ab
XVI.ay
XVI.az
XVI.bj
XVI.bq
XVI.bt
XVI.bx
XVI.ca
XVII.e
XVIII.b
XVIII.j
XVIII.k
XVIII.p
XIX.a
XIX.b
XIX.c
XIX.e
XIX.f
XIX.m
XIX.p
XXVIII.c
Amphetamine (and -derivatives)
I.e
II.a
II.b
III.a
VI.b
VIII.a
XI.r
XII.f
XII.n
XII.af
XIV.a
Aspirin (Salicylate-ASA) - Aspirin containing drugs
I.a
I.c
I.l
II.a
II.b
III.a
III.c
III.m
IV.a
IV.f
V.e
VII.b
VIII.a
VIII.y
X.a
X.f
X.h
X.m
X.q
X.u
XI.b
XI.d
XI.as
XI.az
XII.n
XII.s
XII.af
XV.a
XV.f
XV.w
Beta-blockers
I.a
I.b
I.c
I.d
I.g
I.u
II.a
IV.a
IV.f
IV.ab
IV.ac
V.a
V.c
V.d
VI.w
IX.d
X.d
X.y
XI.r
XI.af
XII.m
XII.n
XII.af
Bisoprolol
IV.a
XII.af
Capecitabine
I.m
VII.a
VIII.af
X.k
XI.b
XII.d
XII.g
XII.af
XII.ai
Capsaicin
IV.q
XII.af
CAR T-cell therapy
I.ao
II.a
II.b
II.r
II.w
III.c
V.a
VI.a
X.an
XII.a
XII.c
XII.f
XII.l
XII.m
XII.n
XII.p
XII.r
XII.af
XII.ah
XII.ai
XII.ba
XII.bt
XII.cd
XVII.b
Carbon monoxide (CO)
II.a
II.b
VI.a
IX.t
X.c
XI.r
XII.f
XII.g
XII.af
XIV.c
XIV.f
XV.w
Carboplatin
II.b
IV.a
X.f
X.g
XI.u
XI.ay
XII.af
Catheter ablation for atrial fibrillation
I.b
I.y
I.ao
II.b
III.a
III.c
III.h
III.l
IV.d
IV.z
IV.ah
V.a
V.e
V.n
VI.b
VI.o
VI.z
VI.ac
VI.ae
VII.d
VII.g
VII.h
VIII.b
VIII.h
VIII.j
IX.j
IX.n
XI.b
XI.k
XII.c
XII.g
XII.y
XII.af
XII.aw
XII.bd
XII.bg
XII.bh
XII.bk
XII.cb
XV.g
XV.ah
XV.ak
XV.cx
XVI.b
XVI.l
XVI.bg
XVI.bo
XVII.a
XXVII.a
Cefuroxime axetil
X.f
XII.af
Cocaine
I.c
I.d
I.e
I.t
I.z
II.a
II.d
III.a
III.b
III.c
III.n
IV.a
IV.f
IV.o
V.f
V.ab
VI.a
VI.b
VI.l
VII.h
VIII.a
VIII.c
VIII.i
VIII.m
VIII.w
VIII.ah
VIII.ai
VIII.ak
VIII.ap
VIII.aw
IX.k
IX.o
X.f
X.h
X.j
X.m
X.o
X.s
X.u
X.x
X.ac
X.ad
X.as
XI.b
XI.m
XI.n
XI.r
XI.ae
XI.az
XII.a
XII.e
XII.f
XII.g
XII.l
XII.y
XII.ae
XII.af
XII.aj
XII.ap
XIV.c
XV.b
XV.g
XV.h
XV.s
XV.w
XV.aw
XVI.k
XVII.b
Dexmedetomidine
XII.m
XII.n
XII.af
XII.ag
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