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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VII.h

Pneumomediastinum

Publications

Galloo X, Stroobants J, Yeo D, El-Abdellati E

Cocaine-Induced Pneumopericardium: Safe for Discharge? A Case Report and Literature Review.

Case reports in cardiology. 2019;2019:4107815

Underner M, Perriot J, Peiffer G

[Pneumomediastinum and cocaine use].

Presse medicale (Paris, France : 1983). 2017;46(3):249-262

Perna V, Vilà E, Guelbenzu JJ, Amat I

Pneumomediastinum: is this really a benign entity? When it can be considered as spontaneous? Our experience in 47 adult patients.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2010;37(3):573-5

Shesser R, Davis C, Edelstein S

Pneumomediastinum and pneumothorax after inhaling alkaloidal cocaine.

Annals of emergency medicine. 1981;10(4):213-5

Seaman ME

Barotrauma related to inhalational drug abuse.

The Journal of emergency medicine. 1990;8(2):141-9