The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Esophageal hematoma (may cause chest pain and/or tracheal compression)
Publications
[Rare but frequently lethal complication of pulmonary vein isolation].
Herzschrittmachertherapie & Elektrophysiologie 2021 Dec;32;463-466 — 2021 Dec — 463-466
[Thoracic air bubbles of unusual cause].
La Revue de medecine interne 2020 Oct;41;714-715 — 2020 Oct — 714-715
Esophageal hematoma complicating catheter ablation for atrial fibrillation.
Journal of cardiovascular electrophysiology 2009 Feb;20;221-3 — 2009 Feb — 221-3