The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Anaphylaxis-Anaphylactoid reaction (can be fatal)
Publications
Two cases of wheat-dependent anaphylaxis induced by aspirin administration but not by exercise.
Clinical and experimental dermatology 2010 Apr;35;233-7 — 2010 Apr — 233-7
Anaphylaxis: a review of 601 cases.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Jul;97;39-43 — 2006 Jul — 39-43