The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pulmonary edema, cardiogenic
Publications
Life-Threatening Accidental Intravenous Epinephrine Overdose in a 12-Year-Old Boy.
Pediatric emergency care. 2019;35(6):e110-e112
Adrenaline in anaphylaxis treatment. Balancing benefits and harms.
Expert opinion on drug safety. 2016;15(6):741-6
Accidental intravenous administration of 50 mg of racemic adrenaline in a 2-year-old boy.
European journal of anaesthesiology. 1995;12(2):181-3
Acute pulmonary edema after regional anesthesia with lidocaine and epinephrine in a patient with chronic renal failure.
Anesthesia and analgesia. 1984;63(3):363-4