The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

L.b

Chest pain (acute or subacute), lone or prominent

Publications

Kim H, Hong B, Kim S, Kang SM, Park J

Chemotherapy-related cardiotoxicity and its symptoms in patients with breast cancer: a scoping review.

Systematic reviews 2024 Jun 27;13;167 — 2024 Jun 27 — 167

Ambrosy AP, Kunz PL, Fisher GA, Witteles RM

Capecitabine-induced chest pain relieved by diltiazem.

The American journal of cardiology 2012 Dec 01;110;1623-6 — 2012 Dec 01 — 1623-6