The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Potolidis E, Mandros C

Carboplatin-induced hypersensitivity reaction.

Case reports in oncology 2012 Jan;5;141-2 — 2012 Jan — 141-2

Winkeljohn D, Polovich M

Carboplatin hypersensitivity reactions.

Clinical journal of oncology nursing 2006 Oct;10;595-8 — 2006 Oct — 595-8

Moreno-Ancillo A, Domínguez-Noche C, Gil-Adrados AC, Cosmes PM, Duarte I, Mateos Y

Anaphylactoid reaction to carboplatin: successful "desensitization".

Allergologia et immunopathologia 2003 Nov-Dec;31;342-4 — 2003 Nov-Dec — 342-4

Markman M, Zanotti K, Kulp B, Peterson G, Markman M

Relationship between a history of systemic allergic reactions and risk of subsequent carboplatin hypersensitivity.

Gynecologic oncology 2003 Jun;89;514-6 — 2003 Jun — 514-6

Windom HH, McGuire WP, Hamilton RG, Adkinson NF

Anaphylaxis to carboplatin--a new platinum chemotherapeutic agent.

The Journal of allergy and clinical immunology 1992 Oct;90;681-3 — 1992 Oct — 681-3