The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.ak

Cardiotoxicity

Publications

Totzeck M, Michel L, Lin Y, Herrmann J, Rassaf T

Cardiotoxicity from chimeric antigen receptor-T cell therapy for advanced malignancies.

European heart journal 2022 Mar 08;; — 2022 Mar 08

Burns EA, Gentille C, Trachtenberg B, Pingali SR, Anand K

Cardiotoxicity Associated with Anti-CD19 Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: Recognition, Risk Factors, and Management.

Diseases (Basel, Switzerland) 2021 Mar 17;9; — 2021 Mar 17