The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Angioedema (may cause UAO, asphyxia and death)
Publications
Isolated periorbital angio-oedema induced by aspirin: a case report and review of the literature.
Dental update. 2007;34(5):302-4
Angioedema associated with aspirin and rofecoxib.
The Annals of pharmacotherapy. 2005;39(5):944-8
Angioedema and acute asthma attack due to the unexpected occurrence of aspirin in an over-the-counter cold preparation.
The British journal of clinical practice. 1996;50(7):412-3
Angioedema and IgE antibodies to aspirin: a case report.
Annals of allergy. 1989;62(4):295-8