The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis
With a predilection for the right phrenic nerve (PMID 29326828)
Publications
Left-sided phrenic nerve injury during redo pulmonary vein isolation long after a previous contralateral self-limiting phrenic nerve palsy.
Clinical case reports 2019 Jul;7;1391-1394 — 2019 Jul — 1391-1394
Abbadessa G, Lavorgna L, Cirillo G, Clerico M, Todisco V, Cirillo M, Trojsi F, Tedeschi G, Bonavita S
Right phrenic nerve palsy following transcatheter radiofrequency current atrial fibrillation ablation: Case report.
The Journal of international medical research 2019 Jul;47;3438-3443 — 2019 Jul — 3438-3443
Second-generation cryoballoon ablation as a first-line treatment of symptomatic atrial fibrillation: Two-year outcome and predictors of recurrence after a single procedure.
International journal of cardiology 2018 05 15;259;76-81 — 2018 05 15 — 76-81
Miyazaki S, Kajiyama T, Watanabe T, Hada M, Yamao K, Kusa S, Igarashi M, Nakamura H, Hachiya H, Tada H, Hirao K, Iesaka Y
Characteristics of Phrenic Nerve Injury During Pulmonary Vein Isolation Using a 28-mm Second-Generation Cryoballoon and Short Freeze Strategy.
Journal of the American Heart Association 2018 Mar 24;7; — 2018 Mar 24
Cryoballoon Ablation in Today's Practice: Can the Left Common Ostium Be Ablated and Injury to the Right Phrenic Nerve Avoided?
Arrhythmia & electrophysiology review 2017 Dec;6;156-158 — 2017 Dec — 156-158
Abugattas JP, de Asmundis C, Iacopino S, Salghetti F, Takarada K, Coutiño HE, Ströker E, De Regibus V, de Greef Y, Brugada P, Sieira J, Chierchia GB
Phrenic nerve injury during right inferior pulmonary vein ablation with the second-generation cryoballoon: clinical, procedural, and anatomical characteristics.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2018 10 01;20;e156-e163 — 2018 10 01 — e156-e163
Abugattas JP, Iacopino S, Moran D, De Regibus V, Takarada K, Mugnai G, Ströker E, Coutiño-Moreno HE, Choudhury R, Storti C, De Greef Y, Paparella G, Brugada P, de Asmundis C, Chierchia GB
Efficacy and safety of the second generation cryoballoon ablation for the treatment of paroxysmal atrial fibrillation in patients over 75 years: a comparison with a younger cohort.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2017 Nov 01;19;1798-1803 — 2017 Nov 01 — 1798-1803
Boveda S, Providência R, Defaye P, Pavin D, Cebron JP, Anselme F, Halimi F, Khoueiry Z, Combes N, Combes S, Jacob S, Albenque JP, Sousa P
Outcomes after cryoballoon or radiofrequency ablation for persistent atrial fibrillation: a multicentric propensity-score matched study.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2016 Nov;47;133-142 — 2016 Nov — 133-142
Ciconte G, Ottaviano L, de Asmundis C, Baltogiannis G, Conte G, Sieira J, Di Giovanni G, Saitoh Y, Irfan G, Mugnai G, Storti C, Montenero AS, Chierchia GB, Brugada P
Pulmonary vein isolation as index procedure for persistent atrial fibrillation: One-year clinical outcome after ablation using the second-generation cryoballoon.
Heart rhythm 2015 Jan;12;60-6 — 2015 Jan — 60-6
Major complications of cryoballoon catheter ablation for atrial fibrillation and their management.
Expert review of cardiovascular therapy 2014 Sep;12;1111-8 — 2014 Sep — 1111-8
Chierchia GB, Di Giovanni G, Ciconte G, de Asmundis C, Conte G, Sieira-Moret J, Rodriguez-Mañero M, Casado R, Baltogiannis G, Namdar M, Saitoh Y, Paparella G, Mugnai G, Brugada P
Second-generation cryoballoon ablation for paroxysmal atrial fibrillation: 1-year follow-up.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2014 May;16;639-44 — 2014 May — 639-44
CT imaging of complications of catheter ablation for atrial fibrillation.
Clinical radiology 2014 Jan;69;96-102 — 2014 Jan — 96-102