The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Alveolar hemorrhage (AH), diffuse AH (DAH)
Publications
Life-threatening pulmonary haemorrhage during cryoballoon ablation for atrial fibrillation.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2018 10 01;54;789-791 — 2018 10 01 — 789-791
Haemoptysis and pulmonary haemorrhage associated with cryoballoon ablation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2015 Aug;17;1240 — 2015 Aug — 1240
Martí-Almor J, Jauregui-Abularach ME, Benito B, Vallès E, Bazan V, Sánchez-Font A, Vollmer I, Altaba C, Guijo MA, Hervas M, Bruguera-Cortada J
Pulmonary hemorrhage after cryoballoon ablation for pulmonary vein isolation in the treatment of atrial fibrillation.
Chest 2014 Jan;145;156-157 — 2014 Jan — 156-157