The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Markou N, Antzoulatos N, Haniotou A, Kanakaki M, Parissis J, Damianos A

A case of drug-induced pneumonitis caused by carvedilol.

Respiration; international review of thoracic diseases 2004 Nov-Dec;71;650-2 — 2004 Nov-Dec — 650-2

Vandezande LM, Gallouj K, Lamblin C, Fourquet B, Maillot E, Wallaert B

[Interstitial lung disease induced by timolol eye solution].

Revue des maladies respiratoires 1999 Feb;16;91-3 — 1999 Feb — 91-3