The Drug-Induced Respiratory Disease Website and App

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.k Epistaxis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.m Coagulopathy

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLV. Pleural and/or pericardial involvement

XLV.e Hemothorax - Serosanguineous pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.x Thoracic epidural or spinal hematoma

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.a DRES syndrome - DRESS-like reaction

LV. Imaging

LV.j Imaging: Wandering (migratory) pulmonary opacities

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.e Pulmonary hematoma

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.k Epistaxis

XLIII. Airway involvement

XLIII.ah Calcification of tracheobronchial cartilaginous rings

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.a Angioedema (may cause UAO, asphyxia and death)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.r Tongue involvement (edema, glossitis, hematoma)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.u Vocal cord hematoma

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.v Retropharyngeal hematoma (may cause UAO)

XLV. Pleural and/or pericardial involvement

XLV.e Hemothorax - Serosanguineous pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVII. Mediastinal involvement

XLVII.g Hemomediastinum - Mediastinal hematoma

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.x Thoracic epidural or spinal hematoma

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.a DRES syndrome - DRESS-like reaction

L. Miscellaneous

L.i Esophageal hematoma (may cause chest pain and/or tracheal compression)

L. Miscellaneous

L.aj Rectus abdominis hematoma

LI. Cardiovascular involvement / toxicity

LI.at Calcification of the coronary artery walls or atheroma

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.d BAL: Gross or microscopic bleeding/hemorrhage

LVII. Cytological, biochemical features of/in BAL, pleural fluid or FNA

LVII.e BAL: Stainable iron in macrophages

LXV. Veterinary medicine

LXV.h Veterinary: Tracheal hemorrhage, stenosis, collapse

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.m Coagulopathy

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.a Angioedema (may cause UAO, asphyxia and death)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVI. Pulmonary vasculopathy

XLVI.a Pulmonary embolism - Venous thrombosis/thromboembolism

LXV. Veterinary medicine

LXV.g Veterinary: Pulmonary bleeding (hemoptysis, alveolar hemorrhage)

LXV. Veterinary medicine

LXV.h Veterinary: Tracheal hemorrhage, stenosis, collapse

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.ap Pulmonary infiltrates

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.a Pulmonary edema, noncardiogenic (NCPE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.p Acute respiratory or cardiopulmonary failure

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.m Coagulopathy

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLVI. Pulmonary vasculopathy

XLVI.a Pulmonary embolism - Venous thrombosis/thromboembolism

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.d Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.w Multiple organ dysfunction/failure (MODS/MOF)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.bb Rhabdomyolysis (see also under Xj)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.h Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

L. Miscellaneous

L.o Death following exposure or poisoning

L. Miscellaneous

L.x CNS symptoms or involvement, stroke

L. Miscellaneous

L.bg Hyperemesis

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.n Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

LI. Cardiovascular involvement / toxicity

LI.al Systemic arterial thrombosis

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.z Progression, acceleration or exacerbation of preexisting ILD/fibrosis

I. Interstitial/parenchymal lung disease

I.ap Pulmonary infiltrates

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.c Hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.h Major/massive hemoptysis

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.l Alveolar hemorrhage, localized (e.g. lobar)

XLIII. Airway involvement

XLIII.n Bronchial wall erosion/hematoma

XLIII. Airway involvement

XLIII.ab Cough (lone)

XLIII. Airway involvement

XLIII.ak Bronchopericardial fistula

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.d Laryngeal disorder-Laryngeal nerve palsy (dysphonia, hoarseness)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.f Vocal cord dysfunction, adduction, closure, injury

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.e Hemothorax - Serosanguineous pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVI. Pulmonary vasculopathy

XLVI.b Pulmonary arterial hypertension

XLVI. Pulmonary vasculopathy

XLVI.o Air/gas embolism

XLVI. Pulmonary vasculopathy

XLVI.y Pulmonary vein stenosis

XLVI. Pulmonary vasculopathy

XLVI.ab Pulmonary infarction

XLVI. Pulmonary vasculopathy

XLVI.ad Pulmonary vein perforation/rupture

XLVII. Mediastinal involvement

XLVII.d Fibrosing mediastinitis

XLVII. Mediastinal involvement

XLVII.g Hemomediastinum - Mediastinal hematoma

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.j Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.n Vagal nerve injury (may cause GE reflux/GERD)

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.i Esophageal hematoma (may cause chest pain and/or tracheal compression)

LI. Cardiovascular involvement / toxicity

LI.c Pericardial effusion (w/wo tamponade)

LI. Cardiovascular involvement / toxicity

LI.h Coronary artery disease (acute) - Myocardial ischemia/infarction

LI. Cardiovascular involvement / toxicity

LI.aa Pneumopericardium

LI. Cardiovascular involvement / toxicity

LI.ah Coronary vasospasm - Vasospastic angina

LI. Cardiovascular involvement / toxicity

LI.ay Postcardiac/-cardiotomy injury (PCIS-Dressler syndrome)

LI. Cardiovascular involvement / toxicity

LI.bg Perforation of the heart - Cardiac rupture

LI. Cardiovascular involvement / toxicity

LI.bj Atrio-esophageal fistula

LI. Cardiovascular involvement / toxicity

LI.bk Atrial septal defect, acquired

LI. Cardiovascular involvement / toxicity

LI.bn Pulmonary vein thrombosis

LI. Cardiovascular involvement / toxicity

LI.bz Pericardial-esophageal fistula

LII. Esophageal involvement

LII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula)

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.l Imaging: Peribronchovascular areas of consolidation

LV. Imaging

LV.bi Imaging: Pulmonary vein stenosis

LV. Imaging

LV.br Imaging: Localized calcification of pulmonary vein or veins

LVIII. Pathology

LVIII.r Path: Alveolar hemorrhage (see also IIIa)

LVIII. Pathology

LVIII.s Path: Pulmonary congestion

LVIII. Pathology

LVIII.bd Path: Pulmonary veno-occlusive disease (PVOD)

LVIII. Pathology

LVIII.da Path: Pulmonary vein stenosis

LIX. Infections & related conditions

LIX.a Respiratory tract infection incl. pneumonia

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.a Pulmonary edema, noncardiogenic (NCPE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.b Pulmonary edema, cardiogenic

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.i Negative pressure pulmonary edema (NPPE)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.c Upper airway obstruction other than angioedema or hematoma

XLV. Pleural and/or pericardial involvement

XLV.f Pneumothorax

XLVII. Mediastinal involvement

XLVII.h Pneumomediastinum

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.ai The serotonin syndrome

L. Miscellaneous

L.h Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

LI. Cardiovascular involvement / toxicity

LI.a Left or biventricular dysfunction/failure

LI. Cardiovascular involvement / toxicity

LI.b Valvular heart disease and/or dysfunction

LI. Cardiovascular involvement / toxicity

LI.d Myocarditis (can be fulminant)

LI. Cardiovascular involvement / toxicity

LI.aa Pneumopericardium

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLV. Pleural and/or pericardial involvement

XLV.e Hemothorax - Serosanguineous pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.n Hemopericardium - Bloody pericardial effusion

XLVI. Pulmonary vasculopathy

XLVI.a Pulmonary embolism - Venous thrombosis/thromboembolism

XLVII. Mediastinal involvement

XLVII.g Hemomediastinum - Mediastinal hematoma

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

L. Miscellaneous

L.i Esophageal hematoma (may cause chest pain and/or tracheal compression)

LI. Cardiovascular involvement / toxicity

LI.w Left-sided intracavitary thrombosis

I. Interstitial/parenchymal lung disease

I.a Pneumonitis (interstitial lung disease/ILD)

I. Interstitial/parenchymal lung disease

I.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

I. Interstitial/parenchymal lung disease

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

I. Interstitial/parenchymal lung disease

I.d Acute eosinophilic pneumonia (AEP)

I. Interstitial/parenchymal lung disease

I.e Organizing pneumonia pattern (an area or areas of consolidation on imaging)

I. Interstitial/parenchymal lung disease

I.g Pulmonary fibrosis

I. Interstitial/parenchymal lung disease

I.m Diffuse alveolar damage (DAD) (see alsoo under IIb and XVf)

I. Interstitial/parenchymal lung disease

I.s An imaging pattern consistent with DIP

I. Interstitial/parenchymal lung disease

I.w Abnormal lung function/pulmonary physiology (PFTs) without necessarily imaging or clinical evidence

I. Interstitial/parenchymal lung disease

I.ay Chronic pneumonitis

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.a Pulmonary edema, noncardiogenic (NCPE)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.d Transient pulmonary opacities/infiltrates (see also under Iav)

XLI. Pulmonary edema - Acute lung injury - ARDS

XLI.e ARDS - Acute lung injury

XLII. Pulmonary/alveolar./airway hemorrhage/bleeding

XLII.a Alveolar hemorrhage (AH), diffuse AH (DAH)

XLIII. Airway involvement

XLIII.a Bronchospasm - Wheezing - Asthma

XLIII. Airway involvement

XLIII.q Tracheobronchitis-like clinical pattern

XLIV. Central-large-upper airway (incl. pharyngeal-nasal) involvement

XLIV.b Hematoma of/around central airway wall potentially causing UAO

XLV. Pleural and/or pericardial involvement

XLV.a Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

XLV. Pleural and/or pericardial involvement

XLV.b Eosinophilic pleural effusion

XLV. Pleural and/or pericardial involvement

XLV.d Pleural/pericardial effusion, ANA positive (DI lupus)

XLV. Pleural and/or pericardial involvement

XLV.i Pleuritis (can cause chest pain)

XLVI. Pulmonary vasculopathy

XLVI.d Pulmonary vasculitis or capillaritis

XLVII. Mediastinal involvement

XLVII.a Lymphadenopathy (intrathoracic)

XLVIII. Neuromuscular / CNS involvement - Disordered breathing (during sleep)

XLVIII.i Respiratory arrest - Apnea

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.a DRES syndrome - DRESS-like reaction

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.d Lupus - Lupus syndrome (see also Vd)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.e Autoimmunity-Autoimmune conditions (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

XLIX. Systemic/Distant conditions, syndromes and reactions

XLIX.u Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

L. Miscellaneous

L.b Chest pain (acute or subacute), lone or prominent

L. Miscellaneous

L.c Pleuritic chest pain

L. Miscellaneous

L.d A restrictive lung function defect

LV. Imaging

LV.b Imaging: Ground-glass opacities (GGO) / shadowing

LV. Imaging

LV.f Imaging: Bibasilar opacities/shadowing

LV. Imaging

LV.l Imaging: Peribronchovascular areas of consolidation

LV. Imaging

LV.be Imaging: Intrathoracic lymph node enlargement

LV. Imaging

LV.bs Imaging: Reverse ventilation-perfusion mismatch

LVIII. Pathology

LVIII.a Path: NSIP-cellular pattern (see also Ia, Ib)

LVIII. Pathology

LVIII.b Path: Eosinophilic pneumonia (subacute or acute) (see also Ic)

LVIII. Pathology

LVIII.d Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

LVIII. Pathology

LVIII.f Path: ILD with a granulomatous component (see also Im)

LVIII. Pathology

LVIII.k Path: Desquamative interstitial pneumonia (DIP-pattern)

LVIII. Pathology

LVIII.l Path: Giant-cell interstitial pneumonia (GIP)-pattern

LVIII. Pathology

LVIII.o Path: Diffuse alveolar damage (DAD-pattern) (see also IL)

LVIII. Pathology

LVIII.p Path: Resolving alveolar damage

LVIII. Pathology

LVIII.v Path: NSIP-fibrotic pattern

LVIII. Pathology

LVIII.w Path: Pulmonary fibrosis (UIP-pattern)

LVIII. Pathology

LVIII.al Path: Acute/subacute bronchiolitis (see also IVc, IVi)

LVIII. Pathology

LVIII.ay Path: Pulmonary vasculitis other than capillaritis

LVIII. Pathology

LVIII.az Path: Granulomatous pulmonary vasculitis