The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.a

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Mohan S, Kumar R, Ish P, Kaushik R, Talukdar T, Gupta N, Gupta N

Diffuse alveolar hemorrhage: a retrospective study from a tertiary care center.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 2024 Oct 28;; — 2024 Oct 28

Oualim S, Elharda CA, Benzeroual D, Hattaoui ME

Pulmonary alveolar hemorrhage mimicking a pneumopathy: a rare complication of dual antiplatelet therapy for ST elevation myocardial infarction.

The Pan African medical journal 2016;24;308 — 2016 — 308

Kim Y, Lim J, Lim J, Kim S, Jung T, Choi W

Pulmonary Alveolar Hemorrhage after Clopidogrel Use for ST Elevation Myocardial Infarction.

Korean circulation journal 2013 Jul;43;497-9 — 2013 Jul — 497-9

Borderías Clau L, Garrapiz López J, Caballero G

[Pulmonary haemorrhage and haemothorax after massive ingestion of clopidogrel as a suicide attempt].

Archivos de bronconeumologia 2009 Nov;45;570-1 — 2009 Nov — 570-1

Gill DS, Ng K, Ng KS

Massive pulmonary haemorrhage complicating the treatment of acute coronary syndrome.

Heart (British Cardiac Society) 2004 Mar;90;e15 — 2004 Mar — e15

Kilaru PK, Schweiger MJ, Kozman HA, Weil TR

Diffuse alveolar hemorrhage after clopidogrel use.

The Journal of invasive cardiology 2001 Jul;13;535-7 — 2001 Jul — 535-7