The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

LVIII.a

Path: NSIP-cellular pattern (see also Ia, Ib)

See under PMID 4827629

Publications

Viejo MA, Fernández Montes A, Montes JV, Gómez-Román JJ, Ibarbia CG, Hernández JL

[Rapid resolution of nitrofurantoin-induced interstitial lung disease].

Archivos de bronconeumologia 2009 Jul;45;352-5 — 2009 Jul — 352-5

Mendez JL, Nadrous HF, Hartman TE, Ryu JH

Chronic nitrofurantoin-induced lung disease.

Mayo Clinic proceedings 2005 Oct;80;1298-302 — 2005 Oct — 1298-302

Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC

Pulmonary drug toxicity: radiologic and pathologic manifestations.

Radiographics : a review publication of the Radiological Society of North America, Inc 2000 Sep-Oct;20;1245-59 — 2000 Sep-Oct — 1245-59