The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.e

Hemothorax - Serosanguineous pleural effusion

Publications

Ganguli A, Walker L, FitzGerald RJ, Pirmohamed M

Spontaneous hemothorax following anticoagulation with low-molecular-weight heparin.

The Annals of pharmacotherapy 2009 Sep;43;1528-31 — 2009 Sep — 1528-31

Robinson NM, Thomas MR, Jewitt DE

Spontaneous haemothorax as a complication of anti-coagulation following coronary angioplasty.

Respiratory medicine 1995 Oct;89;629-30 — 1995 Oct — 629-30