The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Esophageal hematoma (may cause chest pain and/or tracheal compression)
Publications
Massive intramural esophageal hematoma secondary to anticoagulation therapy for mitral valve replacement.
Journal of cardiac surgery 2016 Dec;31;740-741 — 2016 Dec — 740-741
A miniseries of spontaneous intramural esophageal hematoma in hemodialysis patients: a rare cause of dysphagia.
Hemodialysis international. International Symposium on Home Hemodialysis 2014 Apr;18;558-61 — 2014 Apr — 558-61
A rare cause for acute chest pain in the emergency setting that is hard to swallow.
Case reports in emergency medicine 2013;2013;646342 — 2013 — 646342
Intramural oesophageal haematoma complicating anticoagulant therapy.
The New Zealand medical journal 1978 Mar 08;87;176-7 — 1978 Mar 08 — 176-7