The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Organizing pneumonia pattern (an area or areas of consolidation on imaging)
Publications
Nitrofurantoin-induced pulmonary reaction involving respiratory symptoms: case report.
The Canadian journal of hospital pharmacy 2011 Sep;64;362-5 — 2011 Sep — 362-5
Nitrofurantoin-associated bronchiolitis obliterans organizing pneumonia: report of a case.
Canadian respiratory journal 2008 Sep;15;311-2 — 2008 Sep — 311-2
Bronchiolitis interstitial pneumonitis: a pathologic study of 31 lung biopsies with features intermediate between bronchiolitis obliterans organizing pneumonia and usual interstitial pneumonitis, with clinical correlation.
Annals of diagnostic pathology 2008 Jun;12;171-80 — 2008 Jun — 171-80
Drug-associated organizing pneumonia: high-resolution CT findings in 9 patients.
Journal of thoracic imaging 2006 Mar;21;22-6 — 2006 Mar — 22-6